Isoquinoline-or quinoline-sulfonamide derivative and a pharmaceu

Details Isoquinoline-or quinoline-sulfonamide derivative and a pharmaceu Isoquinoline-or quinoline-sulfonamide derivative and a pharmaceu

1990-07-17

1994-08-23

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540553, 540575, 544363, 546140, 546141, 546178, 514218, 514387, 514309, 514311, C07O40112

Patent

active

053408110

ABSTRACT:
Disclosed is a sulfonamide derivative represented by following formula (I) and a medicine for the treatment of asthma comprising the sulfonamide derivative as an active ingredient which exhibits bronchodilation effect. ##STR1## wherein X represents a quinoline residue represented by formula (II) or an isoquinoline residue represented by formula (III) ##STR2## where R.sup.1 is a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group, or ##STR3## where R.sup.2 is a hydrogen atom or a hydroxyl group, and wherein: when X is quinoline residue (II), n is zero or 1, in which,

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