Isoquinoline derivatives, pharmaceutical formulations based on t

Details Isoquinoline derivatives, pharmaceutical formulations based on t Isoquinoline derivatives, pharmaceutical formulations based on t

1983-09-07

1987-06-16

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514222, 514234, 514238, 514253, 544 62, 544128, 544363, 546144, A61K 3147, C07D21716

Patent

active

046736824

ABSTRACT:
Isoquinoline-4-carboxylic acid derivatives of the formula I ##STR1## in which m, n, R.sup.1, R.sup.2, R.sup.3, A and X have the meansings indicated, and physiologically acceptable acid addition salts thereof, a process for their preparation, pharmaceutical formulations based on these compounds and the use thereof as antiarrythmic agents.

REFERENCES:
patent: 4260611 (1981-04-01), Bartmann et al.
Lucas, Organic Chemistry, Sec. Ed., 1953, American Book Co., pp. 61, 175-176.
Nippon Kagaku Zasshi 92, (1971), 1, 80-82.
Tetrahedron Letters 1971, 47, 4503-4506.
Nippon Nogei Kagaku Kaishi 1973, 47, (1), 23-36.
Bl. 1966, 5, 1,763-1,765.
J. of Pharmaceutical Sciences 63, 149, (1974).

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