Isoquinoline derivatives having renal vasodilating properties an

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514252, 514291, 514309, 514310, 544361, 544363, 546 90, 546141, 546143, A61K 31495, C07D40106

Patent

active

048430773

ABSTRACT:
Isoquinoline derivatives of compounds of the general formula ##STR1## that exhibit cardiotonic and/or phosphodiesterase fraction III inhibiting properties and/or renal vasodilating are pharmacologically active in the treatment of cardiac conditions. Methods for synthesizing and using the compounds are described.

REFERENCES:
patent: 3247212 (1966-04-01), Johnson
patent: 3930837 (1976-01-01), Serban
patent: 4590273 (1986-05-01), Konz et al.
Sawanishi, et al., "Chemical Abstracts", vol. 101, 1984, col. 101:151239q.

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