Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-06-13
2006-06-13
Davis, Zinna N. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S307000, C546S147000, C544S315000
Reexamination Certificate
active
07060707
ABSTRACT:
Isoquinoline derivatives of the general formula (I) in which X, Y, Z, R1, R2and n are as defined in Patent Claim (1), and physiologically acceptable salts or solvates thereof, are integrin inhibitors and can be employed for combating thromboses, cardiac infarction, coronary heart diseases, arteriosclerosis, inflammation, tumors, osteoporosis, infections and restenosis after angioplasty or in pathological processes which are maintained or propagated by angiogenesis.
REFERENCES:
patent: 6262069 (2001-07-01), Liebeschuetz et al.
patent: 2002/0055522 (2002-05-01), Liebeschuetz et al.
patent: WO 9911658 (1999-03-01), None
patent: WO 0076971 (2000-12-01), None
patent: WO 0105753 (2001-01-01), None
Goodman Simon
Gottschling Dirk
Kessler Horst
Thumshirn Georgette
Weber Dirk
Davis Zinna N.
Merck Patent GmbH
Miller, White, Zelano & Branigan, P.C.
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