Isoquinoline acetic acids

Details Isoquinoline acetic acids Isoquinoline acetic acids

1979-12-18

1981-08-11

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546142, 546143, 424258, C07D21716, A61K 3147

Patent

active

042835399

ABSTRACT:
Novel isoquinoline acetic acids and derivatives thereof useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications, especially diabetic cataracts are disclosed. Also disclosed are pharmaceutical compositions containing the novel compounds of this invention and a method of treatment of diabetic cataracts by administration of effective amounts of the novel compounds described herein.

REFERENCES:
patent: 4036964 (1977-07-01), Buckle et al.
Maeda et al. Japan Kokai 75 36,470 Apr. 5, 1975, Chem. Abstracts 83 97051S (1975).

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