Isolation, purification, characterization, cloning and sequencin

Details Isolation, purification, characterization, cloning and sequencin Isolation, purification, characterization, cloning and sequencin

1990-06-05

1992-07-07

Wax, Robert A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

4553201, 4552523, 935 11, 935 22, 935 66, C12N 1554, C12N 1581

Patent

active

051284596

ABSTRACT:
This invention is directed to N.sup..alpha. -acetyltransferase with a molecular weight of about 180,000 daltons, said N.sup..alpha. -aceytl-transferase being composed of two subunit peptides having molecular weights of about 95,000 each, having enzyme activity greater than 100 wherein one unit of activity is defined as 1 pmol of acetyl residues incorporated into adrenocorticotropic hormone (ACTH) (amino acids 1-24) under standard assay conditions. This invention is further directed to a method for purifying the N.sup..alpha. -acetyltransferase.

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