Isolation, purification, characterization, cloning and sequencin

Details Isolation, purification, characterization, cloning and sequencin Isolation, purification, characterization, cloning and sequencin

1992-04-03

1994-02-01

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435 691, 4352523, 43525231, 4353201, 536 232, 935 14, 935 28, 935 29, 935 34, 935 39, 935 68, 935 74, C12N 910, C12N 1555, C12N 1574, C12N 1579

Patent

active

052831884

ABSTRACT:
This invention is directed to N.sup..alpha. -acetyltransferase with a molecular weight of about 180,000 daltons, said N.sup..alpha. -acetyltransferase being composed of two subunit peptides having molecular weights of about 95,000 each, having enzyme activity greater than 100 wherein one unit of activity is defined as 1 pmol of acetyl residues incorporated into adrenocorticotropic hormone (ACTH) (amino acids 1-24) under standard assay conditions. This invention is further directed to a method for purifying the N.sup..alpha. -acetyltransferase.

REFERENCES:
patent: 4966848 (1990-10-01), Smith et al.
patent: 5128459 (1992-07-01), Smith et al.

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