Isolation, purification, characterization, cloning and sequencin

Details Isolation, purification, characterization, cloning and sequencin Isolation, purification, characterization, cloning and sequencin

1988-12-14

1990-10-30

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435942, C12N 910

Patent

active

049668480

ABSTRACT:
This invention is directed to N.sup..alpha. -acetyltransferase with a molecular weight of about 180,000 daltons, said N.sup..alpha. -acetyltransferase being composed of two subunit peptides having molecular weights of about 95,000 each, having enzyme activity greater than 100 wherein one unit of activity is defined as 1 pmol of acetyl residues incorporated into adrenocorticotropic hormone (ACTH) (amino acids 1-24) under standard assay conditions. This invention is further directed to a method for purifying the N.sup..alpha. -acetyltransferase.

REFERENCES:
Namboodiri, M. A. A. et al., J. Neurochem. 48:580 (1987).
Glembotski, C. C. et al., J. Biol. Chem. 256:7433-7439 (1981).
Glembotski, C. C. et al., J. Biol. Chem 257:10501-10509 (1982).
Lee, F. S. et al. (1988) J. Biol. Chem. 263 (29), 14948-14955.
Gibson, T. R., et al. (1985) Peptides 6, 615-620.
Namboodiri, M. A. A. et al. (1981) Funct. Regul. Monoamine Enzymes: Basic Clin. Aspects Proc. Conf., 2nd, 701-710.

Affiliated with

Also associated with

Rating

Isolation, purification, characterization, cloning and sequencin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Isolation, purification, characterization, cloning and sequencin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolation, purification, characterization, cloning and sequencin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-274949