Isolation of [S-(R*, S*]-1-(3-acetylthio-3-benzoyl-2-methylpropi

Details Isolation of [S-(R*, S*]-1-(3-acetylthio-3-benzoyl-2-methylpropi Isolation of [S-(R*, S*]-1-(3-acetylthio-3-benzoyl-2-methylpropi

1982-06-28

1984-03-27

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20716

Patent

active

044396112

ABSTRACT:
This disclosure describes continuous epimerization-crystallization process for the isolation of [S-(R*, S*)]-1-(3-acetylthio-3-benzoyl-2-methylpropionyl)-L-proline from a diasteromeric mixture thereof with [S-(R*, R*)]-1-(3-acetylthio-3-benzoyl-2-methylpropionyl)-L-proline.

REFERENCES:
patent: 4226775 (1980-10-01), McEvoy et al.
patent: 4297282 (1981-10-01), Ohashi et al.

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