Isolation of novel HIV-2 proviruses

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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4241601, 435 691, 4353201, 53038835, 536 231, A01N 4304, A61K 3942, C12P 2106, C12N 1500

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active

058830812

ABSTRACT:
Novel HIV-2 proviruses, molecular clones, nucleic acids, polypeptides, viruses and viral components are described. The use of these compositions as components of diagnostic assays, as immunological reagents, as vaccines, as components of packaging cells, cell transduction vectors, and as gene therapy vectors is also described.

REFERENCES:
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patent: 5079342 (1992-01-01), Alizon et al.
Proc. Natl. Acad. Sci. USA, vol. 90, issued May 1993, Talbott, et al., "Mapping the Determinants of Human Immunodeficiency Virus 2 for Infectivity, Replication Efficiency, and Cytopathicity," pp. 4226-4230.
Proc. Natl. Acad. Sci. USA, vol. 86, issued Apr. 1989, Franchini, et al., "Molecular and Biological Characterization of a Replication Competent Human Immunodeficiency Type 2 (HIV-2) Proviral Clone," pp. 2433-2437.
Aids Research and Human Retroviruses, vol. 11, No. 7, issued Jul. 1995, Galabru, et al., "Nucleotide Sequence of the HIV-2 EHO Genome, a Divergent HIV-2 Isolate," pp. 873-874.
Zagury et al., In Vitro Characterization of a Biologically Active Molecular Clone of HIV-2NIH-Z Containing a nef Deletion and Expressing a Full-Length Transmembrane Protein, Aids Research and Human Retroviruses, vol. 6, No. 9, see Abstract, p. 1081, col, 1990.
Garzino-Demo, et al., Human Immunodeficiency Virus Type 2 (HIV-2): Packaging Signal and Associated Negative Regulatory Element, Human Gene Therapy 6:177-184, see Abstract, Feb. 1995.

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