Isolation of macrophage migration inhibition factor from ocular

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.

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530829, 530849, 530412, C07K 302

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053289900

ABSTRACT:
Macrophage Migration Inhibition Factor (MIF) can be obtained from ocular lens of various birds and mammals. The amino acid sequences of lens MIF from mice, chickens and humans has been determined and the corresponding cDNA has been cloned.

REFERENCES:
patent: 4708937 (1987-11-01), Remold
S. O. Stapel et al FEBS Lett. 162(2) 305-309 1983.
G. J. Wistow et al J. Cell Biol. 107:2729-36 1988.
G. J. Wistow et al Nature 326:622-4, 1987.
Weiser et al, Proc. Natl. Acad. Sci. USA, vol. 86, pp. 7522-7526 (1989).
Wistow et al, Ann. Rev. Biochem., vol. 57, pp. 479-504 (1988).

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