Isolation of ibuprofen from tablets

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

Patent

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Details

424484, 424489, 514557, A61K 914, A61K 920

Patent

active

053003012

ABSTRACT:
Ibuprofen is isolated from tablets or other solids by dissolving the ibuprofen in an alkane or cycloalkane solvent, filtering off undissolved solid, and stripping the solvent from the ibuprofen by evaporation or by recrystallization at low temperatures.

REFERENCES:
patent: 4476248 (1984-10-01), Gordon et al.
patent: 5151551 (1992-09-01), Zey et al.
patent: 5189208 (1993-02-01), Stahly

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