Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1995-01-23
1998-05-26
Schwadron, Ronald B.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
435 691, 435 701, 435 711, 435183, 435226, 530413, 530414, 530350, 530415, 530416, 530417, 530418, 530422, 530832, 530419, C07K 114, C07K 116, C07K 130, C07K 136
Patent
active
057566879
ABSTRACT:
Methods of isolating components of interest from a milk sample are described. The methods include a step wherein the solubility of at least a portion of the total milk protein is stabilized in such a manner as to allow isolation of the component of interest without significant loss in yield. Kits for stabilizing the solubility of at least a portion of the total milk protein of the milk sample containing the component of interest also are described.
REFERENCES:
patent: 4644056 (1987-02-01), Kothe et al.
patent: 4898826 (1990-02-01), Duffy et al.
patent: 5165945 (1992-11-01), Yee et al.
patent: 5175013 (1992-12-01), Huang et al.
patent: 5178894 (1993-01-01), Rudel
DiTullio, P. et al. (Jan. 1992) "Production of Cystic Fibrosis Transmembrane Conductance Regulator In The Milk of Transgenic Mice" Bio/Technology, 10:74-77.
Price, N.C., Enzyme Assays--A Practical Approach, "Techniques for Enzyme Extractions" (Oxford University Press 1992) 262-263.
Denman J. et al. (Sep. 1991) "Transgenic Expression Of A Variant Of Human Tissue-Type Plasminogen Activator In Goat Milk: Purification And Characterization Of The Recombinant Enzyme" Bio/Technology, 9:839-843.
Ebert, K.M. et al. (Sep. 1991) "Transgenic Production Of A Variant Of Human Tissue-Type Plasminogen Activator In Goat Milk: Generation Of Transgenic Goats And Analysis Of Expression" Bio/Technology, 9:835-838.
Heng, M.H. and Glatz, C.E. (1990) "Flux Enhancement in Hollow Fiber Ultrafiltration for the Recovery of Acid Cheese Whey Precipitates" Biotechnol. Prog., 6:129-134.
Clark, A.J. et al. (May 1989) "Expression Of Human Anti-Hemophilic Factor IX In The Milk Of Transgenic Sheep" Bio/Technology, 7:487-492.
Gordon, K. et al. (Nov. 1987) "Production Of Human Tissue Plasminogen Activator In Transgenic Mouse Milk" Bio/Technology, 5:1183-1186.
Lau, D. et al. (Sep. 1987) "A Modified Human Tissue Plasminogen Activator With Extended Half-Life In Vivo" Bio/Technology, 5:953-958.
Groves, M.L. and Farrell, H.M. Jr. (1985) "Isolation and Characterization of New Proteins Produced by the Infusion of Colchicine in Goat Mammary Gland" Biochim. et Biophys. Acta, 844:105-112.
Davies, D.T. et al., Biochemistry of Lactation: The Composition of Milk, (ed. Mepham, T.B. Elsevier, NY 1983) 81.
Swaisgood, H.E., Developments in Dairy Chemistry--1. Industrial Isolation of Milk Proteins: Whey Proteins, "Chemistry of Milk Protein" (ed. Fox, P.F., Applied Science Publishers, NY 1982) 339-373.
Steimer, K.S. et al. (1981) "The Serum-Free Growth of Cultured Cells in Bovine Colostrum and in Milk Obtained Later in the Lactation Period" J. Cell Physiol., 109(2):223-234.
Steimer, K.S. and Klagsbrun, M. (Feb. 1981) "Serum-Free Growth of Normal and Transformed Fibroblasts in Milk: Differential Requirements for Fibronectin" J. Cell Biol. 88(2):294-300.
Milk Proteins II--Chemistry and Molecular Biology, "Whole Casein: Isolation, Properties, and Zone Electrophoresis" (ed. McKenzie, H.A., Academic Press, Inc.) 88.
Okamoto et al., Thromb Haemost, 45(2), 121-6, 1981.
Goding, "Monoclonal Antibodies: Principles and Practices", Academic Press, 1986, pp. 109-110.
Christensen et al., Milchwissenschaft, 44:480-484, 1989 (Abstract thereof).
Cole Edward S.
Denman Julie S.
Genzyme Transgenics Corporation
Schwadron Ronald B.
LandOfFree
Isolation of components of interest from milk does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Isolation of components of interest from milk, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolation of components of interest from milk will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1961809