Isolation, characterization, cloning and use of a mushroom...

Details Isolation, characterization, cloning and use of a mushroom... Isolation, characterization, cloning and use of a mushroom...

2005-10-25

2005-10-25

Carlson, Karen Cochrane (Department: 1653)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S350000, C530S395000, C530S413000, C435S007100, C436S172000

Reexamination Certificate

active

06958321

ABSTRACT:
The isolation, characterization, cloning and expression of the lectin (agglutinin) fromMarasmius oreades(MOA) is described. MOA displays unique carbohydrate binding properties, including blood group B-specific agglutination and preferential binding to Ga1α1,3Ga1-containing sugar epitopes, including but not limited to Ga1α1,3Ga1β1,4G1cNAc. MOA is contemplated as an affinity reagent, a therapeutic in the treatment of antibiotic-induced diarrhea and the field of xenotransplantation. MOA may also serve as a diagnostic reagent, e.g. for malaria.

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