Isolation characterization, and use of the human beta subunit of

Details Isolation characterization, and use of the human beta subunit of Isolation characterization, and use of the human beta subunit of

1992-04-16

1998-06-23

Ulm, John

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352523, 4353201, 536 235, 536 243, C12N 510, C12N 1512

Patent

active

057703965

ABSTRACT:
The present invention relates to nucleic acid sequences, encoding amino acid sequences of the .alpha., .beta., and .gamma. subunits of the high affinity receptor for immunoglobulin E, and for amino acid sequences of the subunits. The invention further relates to a method of producing the receptor by expressing cDNA for its .alpha., .beta., and .gamma. subunits in a host cell simultaneously. Aspects of the invention are methods and compositions to inhibit the function of the human beta subunit, thereby treating or preventing allergic reactions.

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