Isolation and use of fibronectin receptor

Details Isolation and use of fibronectin receptor Isolation and use of fibronectin receptor

1993-04-29

1996-07-30

Elliott, George C.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

530395, 514 21, A61K 9127, A61K 3816, C07K 14705

Patent

active

055409334

ABSTRACT:
Method for the isolation and characterization of a 140,000 dalton cell surface glycoprotein with the properties expected of a fibronectin receptor is described.

REFERENCES:
patent: 4483928 (1984-11-01), Suzuta
patent: 4565789 (1986-01-01), Liotta
patent: 4578079 (1986-03-01), Ruoslahti
patent: 4589881 (1986-05-01), Pierschbacher, III
Siancotti et al. 1990. Cell. 60:849-858.
Hynes: Cell 48, pp. 549-554 (1987).
Takada et al.: Nature 326(9), pp. 607-609 (1987).
Horwitz Nature 320, pp. 531-533, 1986.
Gardner Cell 42, pp. 439-448, 1985.
Greve, J. M. and Gottlieb, D. I. (1982) Monoclonal Antibodies Which Alter The Morphology of Cultured Chick Myogenic Cells. J. Cell. Biochem. 18:221-229 (1982).
Horwitz, A., Duggan, K., Greggs, R., Decker, C., and Buck, C. (1985) The Cell Substrate Attachment (CSAT) Antigen Has Properties of a Receptor For Laminin and Fibronectin. J. Cell Biol. 101:2134-2144.
Neff, N. T., Lowrey, C., Decker, C., Tovar, A., Damsky, C., Buck, C., and Horwitz, A. F. (1982) A Monoclonal Antibody Detaches Embryonic Skeletal Muscle From Extracellular Matrices. J. Cell Biol. 95: 654-666.
Horwitz, A., Duggan, K., Buck, C., Beckekle, M. C., and Burridge, K. (1986) Interaction of Plasma Membrane Fibronectin Receptor with Talin--A Transmembrane Linkage. Nature 320:531-533.
Variants Of The Cell Recognition Site of Fibronectin That Retain Attachment-Promoting Activity, M. D. Piersbacher et al. "Proceedings of the National Academy of Sciences USA", vol. 81, pp. 5985-5988 (Oct. 1984).
Cell Attachment Activity of Fibronectin Can Be Duplicated By Small Synthetic Fragments Of the Molecule, M. D. Pierschbacher et al. Nature vol. 309, No. 5963, pp. 30-33 (May 1984).
The Effect of ARG-GLY-ASP-Containing Peptides on Fibronectin and Vol Willebrand Factor Binding to Platelets, E. F. Plow et al. Proc. Natl. Acad. Sci. USA, vol. 82, pp. 8057-8061 (Dec. 1985).
Platelet Membrane Glycoprotein IIb/IIa: Member of a Family of ARG-GLY-ASP-Specific Adhesion Receptors, Robert Pytela et al. Science, vol. 23), pp. 1559-1562 (Mar. 1986).
Inhibition of Fibronectin Binding to Platelets by Proteolytie Fragments and Synthetic Peptides Which Support Fibroblast Adhesion Mark Ginsberg et al. J. of Biological Chemistry, 1985, vol. 260 No. 7, pp. 3931-3936.
Inhibition of Platelet Adhesion to Fibronectin, Fibronectin, and Von Willebrand Factor Substrates by a Synthetic Tetrapeptide Derived From the Cell-Binding Domain of Fibronectin, D. M. Haverstick et. al. Blood- vol. 66 No. 4 (Oct. 1985) pp. 946-952.
The Tetrapeptide Analogue of the Cell Attachment Site of Fibronectin Inhibits Platelet Aggregation and Fibrinogen Binding to Activated Platelets, T. Kent Gartner et al., J. of Biol. Chem. vol. 260, No. 22, pp. 11891-11894 (1985).
Adhesion of Platelets to Laminin in the Absence of Activation, C. R. Ill et al., J. of Cell Biol., vol. 99, pp. 2140-2145 (Dec. 1984).
Lehto, V. P. et al., "Enrichment of A 140 KD Surface Glycoprotein in Adherent, Detergent-Resistant Cytoskeletons of Cultured Human Fibroblasts." Biochemical and Biophysical Res. Comm. 95:909-916 (1980).
Gardner, John M. and Hynes Richard O., "Interaction of Fibronectin with its Receptor on Platelets." Cell 42:439-448 (1985).
Brown, Patricia J. and Juliano, R. L. "Selective Inhibition of Fibronectin-Mediated Cell Adhesion by Monoclonal Antibodies to a Cell-Surface Glycoprotein." Science 228:1448-1451 (1985).
Ginsberg, Mark et al. "Inhibition of Fibronectin Binding to Platelets by Proteolytic Fragments and Synthetic Peptides Which Support Fibroblast Adhesion." J. Biol. Chem. 260:3931-3936 (1985).
Chen, Wen-Tien et al., "Development of Cell Surface Linkage Complexes in Cultured Fibroblasts." J. Cell Biol. 100:1103-1114 (1985).
Pytela, Robert et al., "Identification and Isolation of a 140 kd Cell Surface Glycoprotein with Properties Expected of a Fibronectin Receptor." Cell 40:191-198 (1985).
Ill, Charles R. et al. "Adhesion of Platelets to Laminin in the Absence of Activation." J. Cell Biol. 99:2140-2145 (1984).
Pierschbacher, Michael D. and Ruoslahti, Erkki "Variants of the Cell Recognition Site of Fibronectin that Retain Attachment-Promoting Activity." Proc. Natl. Acad. Sci. USA. 81:5985-5988 (1984).
Pierschbacher, Michael D. and Ruoslahti, Erkki "Cell Attachment Activity of Fibronectin Can Be Duplicated by Small Synthetic Fragments of the Molecule." Nature 309:30-33 (1984).
Pierschbacher, Michael et al. "Synthetic Peptide with Cell Attachment Activity of Fibronectin." Proc. Natl. Acad. Sci. USA. 80:1224-1227 (1983).

Affiliated with

Also associated with

Rating

Isolation and use of fibronectin receptor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Isolation and use of fibronectin receptor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolation and use of fibronectin receptor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1656552