Isolation and structure of spongistatins 5,7,8 and 9

Details Isolation and structure of spongistatins 5,7,8 and 9 Isolation and structure of spongistatins 5,7,8 and 9

1993-07-02

1995-02-28

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D32300

Patent

active

053938976

ABSTRACT:
A Southwest Indian Ocean marine sponge Spirastrella spinispirulifera (bri colored reds and purples) has been found to contain new and exceptionally active cell (human cancer) growth inhibitors spongistatin 5, spongistatin 7, spongistatin 8 and spongistatin 9. These compositions are related to spongistatin 1, which was found in a black Spongia sp. in the Porifera family. A method of treating human cancer cells with spongistatin 5 and spongistatin 7 is also disclosed.

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