Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-01-08
2008-01-08
Aulakh, Charanjit S. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S084000
Reexamination Certificate
active
10546468
ABSTRACT:
Cribrostatin 6, a dark blue cancer cell growth inhibiting constituent of the Republic of Maldives marine sponge Cribrochalina sp. has been isolated, and its structure (shown below) elucidated, based on a combination of RMS, high field (500 MHz, HMBC, and GOESY experiments) 15N,1H- and 13C NMR, and X-ray crystal structure analyses. Cribrostatin 6 also was found to inhibit the growth of a number of pathogenic bacteria and fungi.
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Written Opinion of the International Search Authority for PCT/US04/05163 dated Sep. 2, 2004.
Pettit et al., “Antineoplastic Agents. 485. Isolation and Structure of Cribrostatin 6, a Dark Blue Cancer Cell Growth Inhibitor from the Marine SpongeCribrochalinasp.”,J. Nat. Prod., 66:544-547, 2003.
Knight John C.
Pettit George R.
Arizona Board of Regents, a body corporate of the State of Arizo
Aulakh Charanjit S.
Fennemore Craig P.C.
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