Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-01-08
2008-01-08
Aulakh, Charanjit S. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S084000
Reexamination Certificate
active
07317020
ABSTRACT:
Cribrostatin 6, a dark blue cancer cell growth inhibiting constituent of the Republic of Maldives marine sponge Cribrochalina sp. has been isolated, and its structure (shown below) elucidated, based on a combination of RMS, high field (500 MHz, HMBC, and GOESY experiments) 15N,1H- and 13C NMR, and X-ray crystal structure analyses. Cribrostatin 6 also was found to inhibit the growth of a number of pathogenic bacteria and fungi.
REFERENCES:
patent: 5514689 (1996-05-01), Collins et al.
patent: 6159985 (2000-12-01), Liu et al.
patent: 6437128 (2002-08-01), Pettit et al.
International Search Report for PCT/US04/05163 dated Aug. 9, 2004.
Written Opinion of the International Search Authority for PCT/US04/05163 dated Sep. 2, 2004.
Pettit et al., “Antineoplastic Agents. 485. Isolation and Structure of Cribrostatin 6, a Dark Blue Cancer Cell Growth Inhibitor from the Marine SpongeCribrochalinasp.”,J. Nat. Prod., 66:544-547, 2003.
Knight John C.
Pettit George R.
Arizona Board of Regents, a body corporate of the State of Arizo
Aulakh Charanjit S.
Fennemore Craig P.C.
LandOfFree
Isolation and structure of Cribrostatin 6 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Isolation and structure of Cribrostatin 6, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolation and structure of Cribrostatin 6 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2779593