Isolation and purification of the R18 antigen of HTLV-III

Details Isolation and purification of the R18 antigen of HTLV-III Isolation and purification of the R18 antigen of HTLV-III

1990-07-25

1991-11-05

Moskowitz, Margaret

Drug, bio-affecting and body treating compositions

Lymphokine

530387, 530350, 424 86, A61K 3921, A61K 3942, C07K 1506

Patent

active

050630539

ABSTRACT:
The isolation and purification of a newly discovered gene of the AIDS virus, HTLV-III, which encodes a portein which is immunogenic and recognized by sera of some HTLV-III seropositive people. Furthermore, the gene is highly conserved among all known HTLV-III isolates and exhibits a polymorphism at the 3' end which distinguishes molecular clones of the HTLV-IIIB cell line from viral genomes of related viruses.

REFERENCES:
patent: 4912030 (1990-03-01), Weiss et al.
Pescador et al., Science vol. 227, 484-492.

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