Isolation and production of catalytic antibodies using phage tec

Details Isolation and production of catalytic antibodies using phage tec Isolation and production of catalytic antibodies using phage tec

1994-07-14

1999-01-05

Patterson, Jr., Charles L.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

4351885, 424 941, 4241411, A61K 39395, A61K 3843, A61K 900

Patent

active

058558853

ABSTRACT:
Disclosed and claimed are methods for producing catalytic antibodies, including human catalytic antibodies, from bacteriophage. The methods require the cloning, selection, screening, and isolation of catalytic antibodies. Also disclosed and claimed are the products themselves, the catalytic antibodies, made from the phage technology. In addition, catalytic antibodies produced from the phage technology and useful in prodrug activation are disclosed and claimed. And finally, the invention also understands the production of catalytic antibodies to phosphonates.

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