Multicellular living organisms and unmodified parts thereof and – Nonhuman animal
Patent
1995-06-05
1998-08-04
Stanton, Brian R.
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
4351723, 435 691, 4353201, 435 912, 435 61, 536 231, 424 921, C12N 500, C12N 1500, C12N 1509, C12N 1563
Patent
active
057896518
ABSTRACT:
The present invention relates to the cloning and expression of the Agouti gene and analogous genes in transformed, transfected and transgenic mice. The present invention provides an animal model for the study of diabetes, obesity and tumors for the testing of potential therapeutic agents. The present invention provides oligonucleotide probes for the detection of the Agouti gene and mutations in the gene. The present invention also relates to the isolation and recombinant production of the Agouti gene product, production of antibodies to the Agouti gene product and their use as diagnostic and therapeutic agents.
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Martin Marietta Energy Systems Inc.
Schmuck Jill D.
Stanton Brian R.
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