Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1989-02-02
1992-10-27
Nucker, Christine
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530395, 530829, 530830, 514 8, C07K 1514, A61K 3516
Patent
active
051590638
ABSTRACT:
A substantially pure, single chain plasma protein of approximately 120 kDa having an N-terminal amino acid sequence EKNGIDIYSLTD, and a mixture of protein fragments having vasodilatory activity which fragments are generated by activated Kallikrein cleavage of the 120 kDa protein.
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patent: 4339441 (1982-07-01), Kalman
Ross, G. D. Immunobiology of the Complement System, Academic Press, Inc. New York 1986.
Eldering, E. et al. J. Biol. Chem 263(24):11776-9 Aug. 25, 1988 "Expression of Functional Human C1-".
Hammer, C. H. et al., J. Biol. Chem 264(4):2283-91 Feb. 1989, "Isolation and Characterization . . . ".
Kristensen, T. et al. FASEB Proc. 46(7):2463-69, "The Superfamily of C3b/C4b-binding Proteins", May, 1987.
Basic and Clinical Immunology, Fundenberg, H. H. et al. (editors), see p. 87, Lange Publications, 1980.
Abstract: Hammer, C. H. Jacobs, R. M., Brickman, C. M. and M. M. Frank, A New Human Complement Protein which Co-isolates with C2 (1987), Complement 4:165 (#111).
Frank Michael M.
Hammer Carl H.
Jacobs Ruth M.
Cunningham Thomas
Nucker Christine
The United States of America as represented by the Department of
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