Isolating human antibodies

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S070400, C436S501000

Reexamination Certificate

active

07968308

ABSTRACT:
The invention is drawn to a method of isolating human antibodies.

REFERENCES:
patent: 4458066 (1984-07-01), Caruthers et al.
patent: 4946778 (1990-08-01), Ladner et al.
patent: 5001056 (1991-03-01), Snyder et al.
patent: 5061620 (1991-10-01), Tsukamoto et al.
patent: 5677136 (1997-10-01), Simmons et al.
patent: 5750397 (1998-05-01), Tsukamoto et al.
patent: 6261535 (2001-07-01), Thorpe et al.
patent: WO 90/13678 (1990-11-01), None
patent: WO2004/102198 (2004-11-01), None
Zafiropoulos et al (Journal of Immunological Methods, 1997, vol. 200, pp. 181-190).
Lindhout et al (The Histochemical Journal, 1995, vol. 27, pp. 167-183).
Andersson, E. et al., “A tandem repeat of MUC1 core protein induces a weak in vitro immune response in human B cells,”Cancer Immunology, Immunotherapy, 47(5): 249-256 (1999).
Beaucage, S.L. et al., “Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis,”Tetrahedron Lett., 22(20):1859-1862 (1981).
Benito, A. et al., “Insertion of a 27 amino acid viral peptide in different zones ofEscherichia coliβ-galactosidase: Effects on the enzyme activity.”FEMS Microbiology Letters123:107-112 (1994).
Brown, E.L. et al., “Chemical synthesis and cloning of a tyrosine tRNA gene,” InRecombinant DNA, Methods in Enzymology, 68:109-151 (1979).
Cole, S.P.C. et al. “The EBV-Hybridoma Technique and its Application to Human Lung Cancer.” InMonoclonal Antibodies and Cancer Therapy, edited by R.A. Reisfeld et al., pp. 77-96. New York: A.R. Liss, 1985.
Cote, R.J. et al., “Generation of human monoclonal antibodies reactive with cellular antigens,”Proc. Natl. Acad. Sci. U.S.A., 80(7):2026-30 (1983).
Goldstein, N.I., “An In Vitro Methodology for the Generation of Activated Human B Cells Producing Antibody to Carcinoembryonic Antigen (CEA),”J. Cellular Biochem. Supp., 14, Part B: 81 (1990).
Goodchild, J., “Conjugates of oligonucleotides and modified oligonucleotides: a review of their synthesis and properties,”Bioconjug. Chem., 1(3):65-87 (1990).
Huse, W.D. et al. “Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda,”Science, 246:1275-1281 (1989).
Kantor, A.B. et al., “Development of the Antibody Repertoire as Revealed by Single-Cell PCR of FACS-Sorted B-Cell Subsets,”Annals of the New York Academy of Sciences, 764:224-227 (1995).
Köhler, G. et al., “Continuous cultures of fused cells secreting antibody of predefined specificity,”Nature, 256:495-497 (1975).
Kozbor, D. et al., “The production of monoclonal antibodies from human lymphocytes,”Immunology Today, 4(3):72-79 (1983).
Narang, S.A. et al., “Improved phosphotriester method for the synthesis of gene fragments,”Meth. Enzymol., 68:90-99 (1979).
Petrarca, C. et al. “Isolation of MUC1-primed B lymphocytes from tumour draining lymph nodes by immunomagnetic beads,”Cancer Immunol. Immunother., 47(5):272-277(1999).
Sblattero, D. et al., “A definitive set of oligonucleotide primers for amplifying human V regions,”lmmunotechnology3(4): 271-278 (1998).
Voso, M.T. et al., “Lack of t(14; 18) Polymerase Chain Reaction-Positive Cells in Highly Purified CD34+ Cells and Their CD19 Subsets in Patients With Follicular Lymphoma,”Blood, 89(10):3763-3768 (1997).

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