Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2006-06-27
2006-06-27
Landsman, Robert S. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
07067625
ABSTRACT:
This invention relates to the cloning of a member of a new potassium channel named TWIK-1. More specifically, it relates to an isolated and purified nucleic acid molecule coding for a protein constituting a potassium channel exhibiting the proper-ties and structure of the TWIK-1 type channel, as well as the protein coded by this nucleic acid molecule. The invention also relates to the use of this nucleic acid molecule to transform cells, and the use of these cells expressing the potassium channels exhibiting the properties and structure of the TWIK-1 type channel for the screening of drugs.
REFERENCES:
patent: 5350836 (1994-09-01), Kopchick et al.
patent: WO 94/28131 (1994-12-01), None
patent: WO 95/21943 (1995-09-01), None
Sternson, LA, 1987, New York Academy of Sciences, 507:19-21.
Vukicevic et al. PNAS USA 93:9021-9026, 1996.
Massague J. Cell 49:437-8, 1987.
Pilbeam et al. Bone 14:717-720, 1993.
Skolnick et al. Trends in Biotech. 18:34-39, 2000.
Bork P. Genome Research 10:398-400, 2000.
Doerks et al. Trends in Genetics 14:248-250, 1998.
Smith et al. Nature Biotechnology 15:1222-1223, 1997.
Brenner SE. Trends in Genetics 15:132-133, 1999.
Bork et al. Trends in Genetics 12:425-427, 1996.Bork et al. Trends in Genetics 12:425-427, 1996.
Ketchum, et al., Nature, 376 (6542), Aug. 24, 1995, pp. 690-695.
Lu, et al., Nature, 371 (6494), Sep. 15, 1994, pp. 243-246.
Lesage, et al. The Embo Journal, 15 (5), 1996, pp. 1004-1011.
Lesage, et al., Genomics, 34 (1), 1996, pp. 153-155.
Barhanin Jacques
Duprat Fabrice
Fink Michel
Guillemare Eric
Lazdunski Michel
Centre National de la Recherche Scientifique "CNRS"
DLA Piper Rudnick Gray Cary US LLP
Landsman Robert S.
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