Isolated, truncated nucleic acid molecules which code for gage t

Details Isolated, truncated nucleic acid molecules which code for gage t Isolated, truncated nucleic acid molecules which code for gage t

1996-02-15

2000-05-30

Cunningham, Thomas M.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 693, 4353201, 530395, 536 233, C12N 1512

Patent

active

060690011

ABSTRACT:
A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described. Tumor rejection antigens are also shown.

REFERENCES:
patent: 5610013 (1997-03-01), Van Den Eynde et al.
patent: 5648226 (1997-07-01), Van Den Eynde et al.
Parham, P. et al., Immunol. Rev. 143:141-180, "The origins of HLA-A, -B, -C polymorphism", 1995.
Falk, et al., "Allele-specific peptide ligand motifs of HLA-C molecules", Proc. Natl. Acad. USA 90: 12005-12009 (Dec. 1993).
Rammensee, et al., "MHC Ligands and Peptide Motifs: First Listing", Immunogenetics 41: 178-228 (1995).

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