Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1998-04-22
2000-02-01
McKelvey, Terry
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C07K 1447
Patent
active
060204648
ABSTRACT:
A novel signal transduction factor and a gene encoding the same are provided. The present novel signal transduction factor has, for example, the amino acid sequence set forth in SEQ ID NO: 4, and the DNA sequence encoding the factor has, for example, the sequence set forth in SEQ ID NO: 1.
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Caldwell, Yakubutsu Dotai (Xenobiotic Metabolism and Disposition), vol. 1(1), pp. 119-125 1996.
Ngo et al, The Protein Folding Problem and Tertiary Structure Prediction, Mertz et al (eds.), Birkhauser, Boston, pp. 433 and 492-495, 1994.
Nakao et al, Nature, vol. 389: pp. 631-635, Oct. 9, 1997.
A. Nakao et al., "Identification of Smad2, a Human Mad-related Protein in the Transforming Growth Factor .beta. Signaling Pathway", The Journal of Biological Chemistry, vol. 272, No. 5, pp. 2896-2900, Jan. 1997.
Y. Zhang et al., "The Tumor Suppressor Smad4/DPC4 as a Central Mediator of Smad Function", Current Biology, vol. 7, No. 4, pp. 270-276, Mar. 1997.
Kitamura Koki
Okazaki Kenji
Biomolecular Engineering Research Institute
McKelvey Terry
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