Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-07-04
2006-07-04
Yu, Misook (Department: 1642)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C536S023100, C435S320100, C435S325000, C435S252300, C435S254200
Reexamination Certificate
active
07070954
ABSTRACT:
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human gene (SH3D1A), some polymorphic alleles of which cause susceptibility to cancers hematopoietic disorders and in particular platelet disorders, Down Syndrome, megakaryocytic disorders and leukemia. More specifically, the invention relates to isolated nucleic acid of the human SH3D1A gene, products, and their use in diagnosis and treatments. The invention further relates to the screening of drugs for cancer therapy. Finally, the invention relates to the screening of the SH3D1A gene for mutations, which are useful for diagnosing the predisposition to hematopoietic disorders.
REFERENCES:
patent: WO-96/31625 (1996-10-01), None
Scott et al (Nature Genetics, 1999, 21:440-443).
Skolnick et al. (2000, Trends in Biotech. 18:34-39).
Bork (2000, Genome Research 10:398-400).
Doerks et al. (1998, Trends in Genetics 14:248-250).
Smith et al. (1997, Nature Biotechnology 15:1222-1223).
Brenner (1999, Trends in Genetics 15:132-133).
Bork et al. (1996, Trends in Genetics 12:425-427).
Bowie et al. (1990, Science 247:1306-1310).
Song et al., (Oct. 1999, Nature Genetics, vol. 23, pp. 166-175).
Guipponi et al., (1998, Genomics, vol. 53, pp. 369-376).
OMIM (Online Mendelian Inheritance in Men) with update history of 2002 (with the accession No. #601399 downloaded on Jul. 28, 2004 from url>>ncbi.nlm.nih.gov.
Friedmann (Scientific American, Jun. 1997, pp. 96-101).
Verma and Somia (1997, Nature, vol. 389, pp. 239-242).
Rubanyi (2001, Molecular Aspects of Medicine 22, pp. 113-142).
Chen and Antonarakis (1997, Cytogenetics and Cell Genetics, vol. 78, pp. 213-215).
Definitation of “fluor” in Merriam-Webster Online Dictionary downloaded from url>>m-w.com on Aug. 9, 2004.
Definitation of “-phore” in Merriam-Webster Online Dictionary downloaded from url>>m-w.com on Aug. 9, 2004.
Because Voet et al., (Biochemistry, 1994, p. 815 only).
Voet et al., (Biochemistry, 1994, p. 815 only).
Pucharcós, Carles et al., Alu-splice cloning of humanIntersectin(ITSN), a putative multivalent binding protein expressed in proliferating and differentiating neurons and overexpressed in Down syndrome, European Journal of Human Genetics (1999) 7, 704-712.
Chen Xiao-Ning
Korenberg Julie R.
Chen Xiao-Ning
Korenberg Julie R.
Yu Misook
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