Isolated renal cancer specific antigen

Details Isolated renal cancer specific antigen Isolated renal cancer specific antigen

1998-04-01

2000-08-15

Hutzell, Paula K.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530403, 536 231, C07K 100, C07H 2102

Patent

active

061038733

ABSTRACT:
The invention described methods for identifying a molecule of interest, as well as nucleic acid molecules which encode it, and binding partners for it. A cDNA library from a cell expressing the target is prepared, and expressed in host cells. Lysates of the host cells are screened with a sample, treated to remove interfering binding partners. The treatment involves contact of the sample to lysates of untransfected host cells, and host cells transfected or transformed with the same vector used to make the cDNA library. Also a part of the invention are antigens and cDNA identified using the methodology.

REFERENCES:
patent: 5589579 (1996-12-01), Torczynski et al.

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