Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Patent
1995-06-06
1998-03-17
Hendricks, Keith D.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C12N 906
Patent
active
057285624
ABSTRACT:
This invention relates to an isolated uricase which is stable in an aqueous solution at a temperature up to 60.degree. C. and at a pH of 8.0 for 10 minutes.
REFERENCES:
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patent: 4882280 (1989-11-01), Takashio et al.
patent: 4987076 (1991-01-01), Takashio et al.
L.G. Kral et al, "Cloning a cDNA for Drosphila melanogaster urate oxidase", Gene, vol. 45, 131-173, (1986).
C.C. Lee et al, "Generation of cDNA Probes Directed by Amino Acid Sequence: Cloning of Urate Oxidase", Science, vol. 239, 1288-1291 (1988).
T. Nguyen et al, "Primary structure of the soybean nodulin-35 gene encoding uricase II localized in the peroxisomes of uninfected cells of nodules", Proc. Natl. Acad. Sc., vol. 82, 5040-5044 (1985).
M. Ito et al, "T. Nucleotide sequence of cDNA and predicted amino acid sequence of rat liver uricase", Eur. J. Biochem., vol. 173, 459-463 (1988).
Suggs et al "Use of synthetic oligonucleotides as hybridization Probes . . ", PNAS, vol. 78, No. 11, pp. 6613-6617, (1981).
Young, et al, "Efficient isolation of genes by using antibody probes", PNAS, vol. 80, Mar. 1983, pp. 1194-1198.
Nippon Nogeikagaku Kaishi, vol. 63, No. 3 p. 163 (1989), The Agricultural Society of Japan, Mar. 15, 1989 and English language translation thereof.
Emi Shigenori
Kamimura Minoru
Kikuchi Toshiro
Kojima Yoshio
Shigyo Tatsuro
Hendricks Keith D.
Toyo Boseki Kabushiki Kaisha
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