Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-04-12
1997-10-21
Caputa, Anthony C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
4241851, 4241861, 4242041, 530326, 530350, 530826, G01N 33567, G01N 33566, G01N 33569, C07K 708, C07K 14705, A61K 3810, A61K 3900
Patent
active
056795300
ABSTRACT:
The invention involves an isolated anti prion protein binding protein which has a molecular weight of from about 55 kD to about 65 kD as determined by SDS-PAGE. Also described is a peptide derived from this isolated anti-prion protein binding protein. Diagnostic uses for each of these molecules are discussed.
REFERENCES:
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Elton et al. PNAS 85:2518-2522 Apr. 1988.
Lazar et al. Mol. Cell. Biology 8(3):1247-1252 1988.
Burgess et al. J. Cell Biology 111:2129-37 1990.
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Brentani, "Complementary Hydropathy and the Evolution of Interactive Polypeptides," J. Mol. Evol. 31: 239-243 (1990).
Goldgaber, "Anticipating The Anti-Prion Protein," Nature 351: (May 9, 1991).
Manson, et al., "Anti-prions and other agents," Nature 352: (Jul. 25, 1991).
Hewinson, et al., "Anti-prions and other agents," Nature 352: (Jul. 25, 1991).
Bendheim, et al., "Anti-prions and other agents," Nature 352: 291-292 (Jul. 25, 1991).
Moser, et al., "An anti-prion protein?", Nature 362: 213-214 (Mar. 18, 1993).
Brentani Ricardo Renzo
de Souza Sandro Jose
Caputa Anthony C.
Ludwig Institute for Cancer Research
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