Isolated polypeptide of the stratum corneum and its use

Details Isolated polypeptide of the stratum corneum and its use Isolated polypeptide of the stratum corneum and its use

2006-08-29

2006-08-29

Wax, Robert A. (Department: 1653)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C514S04400A, C536S023500

Reexamination Certificate

active

07098004

ABSTRACT:
The invention concerns an isolated polypeptide, of the family of calcium-fixing proteins, a mixture of polypeptides derived from proteolysis of the isolated polypeptide, compositions containing them, the uses of said polypeptide and a cosmetic treatment method for dry skin, hyperkeratosis, parakeratosis, psoriasis, ichthyosis, and neoplasia. The invention also concerns a deoxyribonucleic acid sequence coding for said polypeptide and the uses of said deoxyribonucleic sequence.

REFERENCES:
patent: 6046315 (2000-04-01), Hillman et al.
patent: 2 716 363 (1998-10-01), None
COMPLETE™, Protease Inhibitor Cocktail Tablets, Roche Diagnostics GmbH, Penzberg, GERMANY.
MULTIPHOR™, Protein Electrophoresis Technical Manual, Amersham Biosciences, Freiburg, GERMANY.
Database EMBL/HINXTON, U.K., “Online” “ni01f09.y5 NCI—CGAP—Br2 Homo sapiens cDNA clone IMAGE:966761 5′ similar to SW: Calm Plafa P24044 CALMDULIN” XP002137649.
B. Mehul et al., “Calmodulin-Like Skin Protein: A New Marker of Keratinocyte Differentiation”, The Society for Investigative Dermatology, Inc., 2001, pp. 905-909, Blackwell Publishing, Malden, MA.
B. Mehul et al., “Identification and Cloning of a New Calmodulin-Like Protein From Human Epidermis”, The Journal of Biological Chemistry, vol. 275, No. 17, Apr. 28, 2000, pp. 12841-12847, Walter de Gruyter, Berlin, Germany.

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