Isolated polynucleotide sequences encoding a fertility...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S320100, C435S069300, C435S455000, C435S471000, C435S325000

Reexamination Certificate

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06891029

ABSTRACT:
The present invention provides an isolated polynucleotide sequence and amino acid sequence for a bovine fertility associated antigen (FAA), methods of producing recombinant bovine FAA protein; methods of increasing the stability of the plasma membrane, acrosome, and/or other portions of a sperm cell by mixing with FAA and/or recombinant FAA protein(s); and increasing fertility of bulls by mixing sperm cells with FAA and/or recombinant FAA protein(s).

REFERENCES:
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Salois et al. Complementary deoxyribonucleic acid cloning and tissue expression of BSP-A3 and BSP-30-kDa: Phosphatidylcholine and heparin-binding proteins of bone seminal plasma. Biol. Reproduction 61:288-297, 1999.*
Rudinger, J. Characteristics of the amino acids as components of a peptide hormone sequence. 1976. In: Peptide Hormones (Parsons, J.A., ed.), University Park Press, Baltimore, pp. 1-7.
Ngo et al. Computational complexity, protein structure prediction, and the Levinthal paradox. 1994. In: The protein folding problem and tertiary structure prediction (Merz et al., eds.); Birkhauser, Boston, pp. 491-495.
Kennell, D.E. Principles and practices of Nucleic acid hybridization. Progr. Nucl. Acid Res. Mol. Biol. 11:259-301, 1971.
McCauley et al., “Purification and Characterization of Fertility-Associated Antigen (FAA) in Bovine Seminal Fluid. Molecular Reproduction and Development” Oct. 1999, vol. 54, pp. 145-153, see entire document.
Bellin et al., Fertility-Associated Antigen on Bull Sperm Indicates Fertility Potential. J. Animal Science. Jul. 1998, vol. 76, pp. 2032-2039, see entire document.

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