Isolated phenylalanine dehydrogenase gene and process for produc

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

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4352523, 43525231, 43525233, 435320, 435108, 4351723, 536 27, 935 1, 935 29, 935 73, 935 74, C12N 902, C12N 1500, C12N 120

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049701576

ABSTRACT:
An isolated gene coding for phenylalanine dehydrogenase of a microorganism belonging to a genus selected from the group consisting of the genera Bacillus and Sporosarcina origin; plasmids containing the gene; microorganism transformed with the plasmid, a process for the production of phenylalanine dehydrogenase using the microogranism; and a process for the production of L-phenylalanine using the enzyme.

REFERENCES:
patent: 4590161 (1986-05-01), Kula et al.
Asano, et al., Eur. J. Biochem. 168:153-150, 1987.
Asano, et al., Agric. Biol. Chem. 51(9):2621-2623, 1987.
Patent Abstracts of Japan, vol. 9, No. 138 (C-286) (1861), Jun. 13, 1985, JP 60-24192(A).
Ozaki et al., "Cloning and Nucleotide Sequencing of Phenylalanine Dehydrogenase Gene of Bacillus sphaericus", Gene, vol. 63, No. 2, pp. 337-341 (1988)
Asano et al., "Novel Phenylalanine Dehydrogenases from Sporosarcina ureae and Bacillus sphaericus," The Journal of Biological Chemistry, vol. 262, No. 21, pp. 10346-10354, Jul. 25, 1987.

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