Isolated phages and their use in food or pet food products

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...

Reexamination Certificate

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Reexamination Certificate

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10864604

ABSTRACT:
The present invention relates to phage isolates having a strong lytic activity against pathogenic Enterobacteriaceae such asEscherichia coliand/orSalmonellastrains and their use in various human or pet food products for the treatment or prevention of bacterial diseases caused by pathogenic Enterobacteriaceae such asEscherichia coli, in particular for phage therapy of pediatric gastroenteritis, orSalmonellainfection. It also relates to human or pet food products prepared thereof.

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Berchieri, A. Jr. et al.,“The Activity in the Chicken Alimentary Tract of Bacteriophages Lytic ForSalmonellaTyphimurium,”Research in Microbiology,vol. 142, No. 5, pp. 541-549 (1991).
Blattner, F. R. et al., “The Complete Genome Sequence ofEscherichia ColiK-12,”Science,vol. 277, pp. 1453-1474 (1997).
Hayashi, T. et al., “Complete Genome Sequence of EnterohemorrhagicEschelichia coliO157:H7 and Genomic Comparison With a Laboratory Strain K-12,”DNA Research,vol. 8, pp. 11-22 (2001).
Perna, N. T. et al., “Genome sequence of enterohaemorrhagicEscherichia coliO157:H7,”Nature,vol. 409, pp. 529-533 (2001).
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Smith, H. W. et al., “The Control of experimentalEscherichia ColiDiarrhoea in Calves by Means of Bacteriophages,”J. Gen. Microbiol.,vol. 133, No. 5, pp. 1111-1126 (1987).

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