Isolated peptides derived from tumor rejection antigens, and the

Details Isolated peptides derived from tumor rejection antigens, and the Isolated peptides derived from tumor rejection antigens, and the

1995-01-10

1997-07-15

Cunningham, Thomas M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 723, 4241851, 4242771, 530326, 530327, 530328, 530828, G01N 33574, C07K 1482, C07K 700

Patent

active

056482264

ABSTRACT:
A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described. Tumor rejection antigens are also shown.

REFERENCES:
Falk, et al., "Allele-specific peptide ligand motifs of HLA-C molecules", Proc. Natl. Acad. Sci. USA 90: 12005-12009 (Dec. 1993).
Ramensee, et al., "MHC Ligands and Peptide Motifs: First Listing", Immunogenetics 41: 178-228 (1995).
Herin et al., "Production of Stable Cytolytic T-Cell Clones Directed Against Autologous Human Melanoma", Int. J. Cancer 39: 390-396 (1987).
Wolfel et al., "Lysis of Human Melanoma Cells By Autologous Cytolytic T Cell Clones", J. Exp. Med. 170: 797-810 (Sep. 1989).
Van Den Eynde et al., "Presence On a Human Melanoma of Multiple Antigens Recognized by Autologous CTL", Int. J. Cancer 44: 634-640 (1989).
Van der Bruggen, et al., "A Gene Encoding An Antigen Recognized By Cytolytic T Lymphocytes on a Human Melanoma", Science 254: 1643-1647 (Dec. 1991).
Brasseur et al., "Human Gene MAGE-1, which codes for a tumor rejection antigen, is expressed by some breast tumors", Int. J. Cancer 52: 839-841 (1992).
Traversari et al., "Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes", Immunogenetics 35: 145-152 (1992).
Traversari et al., "A Nonapeptide Encoded by Human Gene MAGE-1 Is Recognized on HLA-A1 By Cytolytic T Lymphocytes Directed Against Tumor Antigen MZ2-E", J. Exp. Med. 176: 1453-1457 (Nov. 1992).

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