Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-09-21
1999-01-12
Cunningham, Thomas M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
530300, 530328, C12Q 100, C07K 700
Patent
active
058586890
ABSTRACT:
A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described. Tumor rejection antigens are also shown.
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Toubert, et al., "HLA-A29 Peptide Binding Motif", Abstract No. 4183, Ninth International Congress of Immunology, Jul. 23-Jul. 29, 1995.
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Engelhard, "Structure of Peptides Associated with Class I and Class II MHC Molecules", Ann. Rev. Immunol, 1994.
Rammensee, et al., "MHC ligands and peptide motifs: first listing ", Immunogenetics 41; 178-228, 1995.
Boon-Falleur Thierry
DeBacker Olivier
Van den Eynde Benoit
van der Bruggen Pierre
Cunningham Thomas M.
Ludwig Institute for Cancer Research
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