Isolated peptides derived from the gage tumor rejection antigen

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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530300, 530328, C12Q 100, C07K 700

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active

058586890

ABSTRACT:
A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described. Tumor rejection antigens are also shown.

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Toubert, et al., "HLA-A29 Peptide Binding Motif", Abstract No. 4183, Ninth International Congress of Immunology, Jul. 23-Jul. 29, 1995.
Zemmour, "HLA class I nucleotide sequences, 1993", Immunogenetics 37: 239-250, 1993.
Engelhard, "Structure of Peptides Associated with Class I and Class II MHC Molecules", Ann. Rev. Immunol, 1994.
Rammensee, et al., "MHC ligands and peptide motifs: first listing ", Immunogenetics 41; 178-228, 1995.

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