Isolated peptides derived from human immunodeficiency virus type

Details Isolated peptides derived from human immunodeficiency virus type Isolated peptides derived from human immunodeficiency virus type

1995-06-07

2000-02-01

Scheiner, Laurie

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

530324, 530325, 530326, 530350, 4241881, A61K 3800, A61K 3921

Patent

active

060204591

ABSTRACT:
The present invention relates to peptides which exhibit potent anti-retroviral activity. The peptides of the invention comprise DP178 (SEQ ID:1) peptide corresponding to amino acids 638 to 673 of the HIV-1.sub.LAI gp41 protein, and fragments, analogs and homologs of DP178. The invention further relates to the uses of such peptides as inhibitory of human and non-human retroviral, especially HIV, transmission to uninfected cells.

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