Isolated peptide which binds to HLA-Cw*07 and uses thereof

Details Isolated peptide which binds to HLA-Cw*07 and uses thereof Isolated peptide which binds to HLA-Cw*07 and uses thereof

2004-09-15

2009-02-10

Blanchard, David J (Department: 1643)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

C514S002600, C514S013800, C514S014800

Reexamination Certificate

active

07488793

ABSTRACT:
Peptides which consist of amino acid sequences found in MAGEA3 bind to HLA-Cw*07 molecules to form T cell epitopes. The therapeutic and diagnostic ramifications of this are the subject of this invention, as are various products obtained in the course of the development of the invention.

REFERENCES:
patent: WO/99/45954 (1999-09-01), None
patent: WO0142267 (2001-06-01), None
patent: WO/01/90197 (2001-11-01), None
Steve Pascolo et al., “A Mage-A1 HLA-A*0201 Epitope Identified by Mass Spectrometry,”Cancer Research, 61:4072-4077 (2001).
Sacha Gnjatic et al., “Cross-Presentation of HLA Class I Epitopes from Exogenous NY-ESO-1 Polypeptides by Nonprofessional APCs,”The Journal of Immunology, 170:1191-1196 (2003).

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