Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1990-02-27
1993-01-05
Lacey, David L.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
536 235, 530350, 530399, 435 691, 4352402, 4353201, C07H 1512, C07H 1700, A61K 3724, C12P 2106
Patent
active
051771977
ABSTRACT:
Purified protein known as platelet TGF-.beta.1-BP (transforming growth factor-.beta.1-binding protein) is described. The protein is useful for purposes such as the production of antisera which are useful in identifying complexes containing the binding protein, as well as in formation of labeled probes. Also described are purified DNA which expresses the protein, as well as messenger RNA translated into the protein. The protein contains 16 epidermal growth factors (EGF) like repeats, and 3 repeats not found in other proteins. The DNA for the protein is found to contain consensus sequences for hydroxylation of asparagine/aspartic acid residues, and, in the purified protein beta hydroxylated asparagine residues were found.
REFERENCES:
Lee et al., (1988), Science, vol. 239: pp. 1288-1291.
Miyazono et al., Nature, 338: 158-160 (Mar. 9, 1989).
Miyazono et al., J. Biol. Chem., 263(13): 6407-6415 (1988).
Hynes, Cell, 48: 549-554 (1987).
Claesson-Welsh Lena
Heldin Carl-Henrik
Hellman Ulf
Kanzaki Tetsuto
Miyazono Kohei
Lacey David L.
Ludwig Institute for Cancer Research
Wang Gian P.
LandOfFree
Isolated nucleotide sequence expressing human transforming growt does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Isolated nucleotide sequence expressing human transforming growt, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolated nucleotide sequence expressing human transforming growt will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2391427