Isolated nucleic acids encoding CYP7 promoter-binding factors

Details Isolated nucleic acids encoding CYP7 promoter-binding factors Isolated nucleic acids encoding CYP7 promoter-binding factors

1998-08-11

1999-09-28

McKelvey, Terry

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 691, 435243, 4353201, 435325, 435410, 536 235, C12Q 168, C12N 100, C12N 510, C12N 1512, C12N 1563, C12P 2102

Patent

active

059586974

ABSTRACT:
The invention provides methods and compositions relating to CPF proteins which regulate transcriptional activation, and related nucleic acids. The polypeptides may be produced recombinantly from transformed host cells from the disclosed CPF encoding nucleic acids or purified from human cells. The invention provides isolated CPF hybridization probes and primers capable of specifically hybridizing with the disclosed CPF genes, CPF-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.

REFERENCES:
Kudo et al. Molecular cloning of chicken FTZ-F1-related orphan receptors. Gene. Sep. 15, 1997, vol. 197, No. 1/2, pp. 261-268.
Ellinger-Zeigelbauer et al, Molecular and Cellular Biology, vol. 14, No. 4: pp. 2786-2797, Apr. 1994.

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