Isolated nucleic acid molecules which encode mammalian .alpha.2,

Details Isolated nucleic acid molecules which encode mammalian .alpha.2, Isolated nucleic acid molecules which encode mammalian .alpha.2,

1995-07-17

1998-05-05

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4352523, 43525233, 435193, 4353201, 435 691, 536 232, 536 235, 530350, C12N 1500, C12N 1563, C12N 910, C07H 2104

Patent

active

057473269

ABSTRACT:
Isolated nucleic acid molecules encoding polysialyl transferases, and the polysialyl transferases themselves are disclosed. SEQ ID NOS: 1, 2, 7 and 8 present examples of these. The nucleic acid molecules and the proteins can be used diagnostically or therapeutically. Additionally, antisense oligonucleotides and antibodies are described, which can also be used diagnostically or therapeutically.

REFERENCES:
Eckhardt et al. Nature, 373:715-718, Feb. 23, 1995.
Steenbergen et al. J. Bacteriol., 174(4):1099-1108, Feb. 1, 1992.
Sasaki et al. J. Biol. Chem., 269(22):15950-15956, Jun. 3, 1994.

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