Isolated nucleic acid molecules useful in determining expression

Details Isolated nucleic acid molecules useful in determining expression Isolated nucleic acid molecules useful in determining expression

1994-09-01

1997-03-18

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 6, 536 231, 536 2433, C12P 1934, C12Q 168, C07H 2102, C07H 2104

Patent

active

056122012

ABSTRACT:
The invention relates to nucleic acid molecules which are useful in determining expression of the family of molecules known as the MAGE tumor rejection antigen precursors. These nucleic acid are molecules useful as diagnostic aids for determining whether or not an individual has cancer. Methods using these molecules are also described.

REFERENCES:
patent: 5342774 (1994-08-01), Boon et al.
Van der Bruggen et al., "A Gene Encoding an Antigen Recognized By Cytolytic T Lymphocytes on Human Melanoma", Science 254: 1643-1657 (Dec. 1991).
Brasseur et al., "Human gene MAGE-1, which codes for a tumor rejection antigen, is expressed by some breast tumors", Int. J. Cancer 42: 839-841 (1992).
DeSmet et al., "Sequence and expression pattern of the human MAGE 2 gene", Immunogenetics 39: 121-129 (1994).
Gaugler et al., "Human Gene MAGE-3 Codes For An Antigen Recognized on a Melanoma by Autologous Cytolytic T Lymphocytes", J. Exp. Med. 179: 921-930 (Mar., 1994).

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