Isolated nucleic acid molecule encoding human skeletal muscle-sp

Details Isolated nucleic acid molecule encoding human skeletal muscle-sp Isolated nucleic acid molecule encoding human skeletal muscle-sp

1999-03-22

2000-12-26

Schwartzman, Robert A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 235, C07H 2100, C07H 2104

Patent

active

061661902

ABSTRACT:
An isolated nucleic acid molecule encoding human skeletal muscle-specific ubiquitin-conjugating enzyme and comprising a nucleotide sequence coding for the amino acid sequence shown in SEQ ID NO:22 is disclosed. The isolation of this molecule makes it possible to detect its expression in various tissues, analyze its structure and function, and produce the human proteins encoded by this molecule by the technology of genetic engineering. In this way, it is possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the molecule, for example hereditary diseases and cancer, and diagnose and treat such diseases.

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