Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1998-01-26
2000-05-30
Zitomer, Stephanie
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530806, 930DIG530, C07K 14435
Patent
active
060692332
ABSTRACT:
The invention relates to the isolation of a nucleic acid molecule which encodes an esophageal cancer associated antigen. Also a part of the invention is the antigen itself, and the uses of the nucleic acid molecule and the antigen.
REFERENCES:
patent: 5212085 (1993-05-01), Wands et al.
Chen et al., "A testicular antigen aberrantly expressed in human-cancers detected by autologous antibody screening," Proc. Natl. Acad. Sci. USA, 94:1914-1918 (Mar. 1997).
Kiyokawa et al., "Overexpression of ERK, an EPH Family Receptor-Protein Tyrosine Kinase, in Various Human Tumors," Canc. Res., 54:3645-3650 (Jul. 15, 1994).
Fazioli et al., "The ezrin-like family of tyrosine kinase subtrates: receptor specific pattern of tyrosine phosphorylation and relationship to malignant transformation," Oncogene, 8(5):1335-1345(May 1993).
Chen Yao-tseng
Gure Ali O.
Old Lloyd J.
Pfreundschuh Michael
Sahin Ugur
Cornell Research Foundation
Ludwig Institute for Cancer Research
Memorial Sloan-Kettering Cancer Center
Zitomer Stephanie
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