Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2009-07-02
2011-12-06
Chandra, Gyan (Department: 1646)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S069100
Reexamination Certificate
active
08071746
ABSTRACT:
Disclosed herein are peptides or peptide analogs with multiple amphipathic α-helical domains that promote lipid efflux from cells via an ABCA1-dependent pathway. Also provided herein are methods of using multi-domain amphipathic α-helical peptides or peptide analogs to treat or inhibit dyslipidemic disorders. Methods for identifying non-cytotoxic peptides that promote ABCA1-dependent lipid efflux from cells are also disclosed herein.
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Amar Marcele J. A.
Brewer Bryan H.
Demosky Stephen J.
Neufeld Edward B.
Remaley Alan T.
Chandra Gyan
Klarquist & Sparkman, LLP
The United States of America as represented by the Secretary, De
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