Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-11-12
1995-12-19
Parr, Margaret
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4351723, 4353201, 4352523, 435 912, 536 237, 536 2432, 935 77, 935 78, 935 6, 935 22, 436 94, C07H 2102, C07H 2104, C12Q 168, C12N 510
Patent
active
054767679
ABSTRACT:
The invention relates to isolated nucleic acid molecules coding for toxins associated with Kawasaki Syndrome. Also described are various applications of the nucleic acid molecules.
REFERENCES:
patent: 4731245 (1988-03-01), Tsurumizu et al.
patent: 5075236 (1991-12-01), Yone et al.
Schlievert, "Role of Superantigens in Human Disease", J. Infect. Dis. 167: 997-1002 (1993).
Miethke et al., "Pathogenesis of the toxic shock syndrome: T cell mediated lethal shock caused by the superantigen TSST-1", Eur. J. Immuno. 23: 1494-1500 (1993).
Abe et al., "Selective expansion of T cells expressly T-cell receptor variable regions VB2 and VB8 in Kawasaki disease", Proc. Natl. Acad. Sci. USA 89: 4066-4070 (May, 1992).
Choi et al., "Selective Expansion of T cells Expressing V.beta.2 in Toxic Shock Syndrome", J. Exp. Med. 172: 981-984 (Sep. 1990).
Schulman et al., "Management of Kawasaki syndrome: a consensus statement prepared by North American participants of The Third International Kawasaki Disease Symposium, Tokyo, Japan, Dec., 1988", Pediatr. Infect. Dis. J. 8: 663-665 (1989).
Feigin et al., ed., Textbook of Pediatric Infectious Diseases (vol. II, third edition), pp. 1254-1257.
Barsuiman et al., "Heterogeneity of Group A Streptococcal Pyrogenic Endotoxin Type B", Infect. & Immunol. 20(2): 512-58 (May 1978).
Leung et al., "Endothelial Cell Activation and High Interleukin-1 Secretion In The Pathogenesis of Acute Kawasaki Disease", Lancer (Dec. 2, 1989), pp. 1289-1303.
Sheagren, "Staphylococcus Aureus The Persistent Pathogen", N. Eng. J. Med. 310(21): 1368-1372 (May 24, 1984).
Sheargren, "Staphylococcus Aureus The Persistent Pathogen" 310(22): 1437-1442 (May 31, 1984).
Schlievert et al., "Production of Staphylococcal Pyrogenic Exotoxin Type C: Influence of Physical and Chemical Factors", J. Infect. Dis. 147(2): 236-242 (Feb. 1983).
Schlievert et al., "Purification and Physiocochemical and Biological Characterization of a Staphylcoccal Pyrogenic Exotoxin", Infect. & Immunol. 23(3): 609-617 (Mar. 1979).
Lee et al J Infect Dis (1992) 165:1056-1063.
Blomster-Hautamaa et al J Biol Chem (1986) 261: 15783-15786.
Melish et al, The American Pediatric Society & Society for Pediatric Research, 1994, p. 187A, Abstract No. 1107.
Fulton David
Leung Donald
Meissner Cody
Schlievert Patrick
Myers Carla
National Jewish Center for Immunology and Respiratory Medicine
New England Medical Center Hospital, Inc.
Parr Margaret
Regents of the University of Minnesota
LandOfFree
Isolated nucleic acid molecule coding for toxin associated with does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Isolated nucleic acid molecule coding for toxin associated with , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolated nucleic acid molecule coding for toxin associated with will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-991547