Isolated nucleic acid encoding corticotropin-releasing factor.su

Details Isolated nucleic acid encoding corticotropin-releasing factor.su Isolated nucleic acid encoding corticotropin-releasing factor.su

1995-01-31

1998-07-28

Ulm, John

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 691, 4353201, 536 235, 530350, C07K 14705, C12N 510, C12N 1512

Patent

active

057862036

ABSTRACT:
The present invention provides isolated nucleic acid molecules encoding CRF.sub.2 receptors, recombinant expression vectors and host cells suitable for expressing such receptors, as well as compositions and methods which utilize such receptors.

REFERENCES:
Chang et al., "Identification of a Seven Transmembrane Helix Receptor for Corticotropin-Releasing Factor and Sauvagine in Mammalian Brain," Neuron 11:1187-1195, 1993.
Vita et al., "Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors," FEBS Letters 335(1): 1-5, 1993.
Chen et al., "Expression cloning of a human corticotropin-releasing-factor receptor," Proc. Natl. Acad. Sci. 90:8967-8971, 1993.
Perrin et al., "Cloning and Functional Expression of a Rat Brain Corticotropin Releasing Factor (CRF) Receptor," Endocrinology 133(6): 3058-3061, 1993.
Lovenberg et al., "Cloning and characterization of a functionally distinct corticotropin releasing factor receptor subtype from rat brain," Proc. Natl. Acad. Sci. 92:836-840, 1995.
Stenzel et al., "Identification of a Novel Murine Receptor for Corticotropin-Releasing Hormone Expressed in the Heart," Molecular Endocrinology 9(5): 637-645, 1995.
De Souza, E., "Corticotropin-Releasing Factor Receptors in the Rat Cental Nervous System: Characterization and Regional Distribution," Journal of Neuroscience 7(1): 88-100, 1987.

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