Isolated mevalonate pathway enzyme nucleic acids

Details Isolated mevalonate pathway enzyme nucleic acids Isolated mevalonate pathway enzyme nucleic acids

2006-09-01

2010-02-23

Fronda, Christian L (Department: 1652)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S041000, C435S132000, C435S183000, C435S189000, C435S194000, C435S232000, C435S252300, C435S320100

Reexamination Certificate

active

07667017

ABSTRACT:
Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate. A related method comprises introducing into a host microorganism an intermediate in the mevalonate pathway and at least one heterologous nucleic acid sequence, each sequence coding for an enzyme in the mevalonate pathway necessary for converting the intermediate into isopentenyl pyrophosphate. The invention also provides nucleic acid sequences, enzymes, expression vectors, and transformed host cells for carrying out the methods.

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66 FR 1099, Friday, Jan. 5, 2001.
BLAST 2 Sequences results. Sequence 1 gi 5531936, Sequence 2 gi 546900, printed on Jun. 24, 2005.
Hiser et al., 

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