Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-03-24
1996-09-10
Cunningham, Thomas M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
4241851, 4241931, 4242771, 4352402, 514 2, 514 15, 530300, 530328, 530828, G01N 33567, G01N 33574, C07K 700
Patent
active
055545068
ABSTRACT:
Tumor rejection antigens derived from tumor rejection precursor MAGE-3 have been identified. These "TRAS" bind to the MHC-class I molecule HLA-A2, and the resulting complexes stimulate the production of cytolytic T cell clones which lyse the presenting cells. The peptides and complexes may be used diagnostically, therapeutically, and as immunogens for the production of antibodies, or as targets for the generation of cytolytic T cell clones.
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Boon-Falleur Thierry
Fleischauer Katharina
Traversari Catia
van der Bruggen Pierre
Cunningham Thomas M.
Ludwig Institute for Cancer Research
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